Genetic manipulation of palmitoylethanolamide production and inactivation in Saccharomyces cerevisiae.
(2009) PLoS One — Vol. 4, n° 6, p. e5942 (2009)
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- Abstract
- Lipids can act as signaling molecules, activating intracellular and membrane-associated receptors to regulate physiological functions. To understand how a newly discovered signaling lipid functions, it is necessary to identify and characterize the enzymes involved in their production and inactivation. The signaling lipid N-palmitoylethanolamine (PEA) is known to activate intracellular and membrane-associated receptors and regulate physiological functions, but little is known about the enzymes involved in its production and inactivation.
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Citations
Muccioli, G., Sia, A., Muchowski, P. J., & Stella, N. (2009). Genetic manipulation of palmitoylethanolamide production and inactivation in Saccharomyces cerevisiae. PLoS One, 4(6), e5942. https://doi.org/10.1371/journal.pone.0005942 (Original work published 2009)