Biologically active γ-lactams: synthesis and natural sources

Caruano, Joséphine; Muccioli, Giulio; Robiette, Raphaël

doi:10.1039/C6OB01349J

Biologically active γ-lactams: synthesis and natural sources

Caruano, Joséphine

;

Muccioli, Giulio

;

Robiette, Raphaël

(2016) Organic & Biomolecular Chemistry — Vol. 14, n° 43, p. 10134-10156 (2016)

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Authors

Caruano, JoséphineUCLouvain
Author
Muccioli, GiulioUCLouvain
Author
Robiette, RaphaëlUCLouvain
Author

Abstract

The γ-lactam moiety is present in a large number of natural and non-natural biologically active compounds. The range of biological activities covered by these compounds is very broad. Functionalized γ-lactams are thus of high interest and have great potential in medicinal chemistry. This review provides a description of the title compounds by focusing on their synthesis, natural sources and biological activities.

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UCLouvainSST/IMCN/MOST - Molecular Chemistry, Materials and Catalysis

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Caruano, J., Muccioli, G., & Robiette, R. (2016). Biologically active γ-lactams: synthesis and natural sources. Organic & Biomolecular Chemistry, 14(43), 10134-10156. https://doi.org/10.1039/C6OB01349J (Original work published 2016)