Megakaryocytopoiesis: growth factors, cell cycle and gene expression.
(1998) Anticancer Research : international journal of cancer research and treatment — Vol. 18, n° 3B, p. 1871-1882 (1998)
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- Abstract
- Megakaryocytopoiesis is the process prior to the release of platelets into the blood vessel. It is regulated by a variety of cell-cell interactions and a number of cytokines with either stimulatory or inhibitory effects. It is the intent of this review to give an overview of the regulation of megakaryocytopoiesis in a comprehensive analysis of the most recent advances, with special emphasis on cytokines that stimulate or inhibit megakaryocytopoiesis and on the cell cycle and gene expression of megakaryocytes. A chapter will be devoted to the abnormal megakaryocytopoiesis in hematological diseases and, in particular, in myeloproliferative syndromes.
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Baatout, S. (1998). Megakaryocytopoiesis: growth factors, cell cycle and gene expression. Anticancer Research : international journal of cancer research and treatment, 18(3B), 1871-1882. https://hdl.handle.net/2078.5/44566 (Original work published 1998)