Fourier transform infrared spectra of 75 biopsies from 55 cases of breast carcinoma were studied in comparison with histo-morphometry, The spectra of carcinomatous tissues are very different from those of normal tissues. There are evident correlations between the intensity of some infrared absorption bands and the volume density of malignant cells measured by optical microscopy [7]. Very high correlation coefficients are observed for phosphate monoester and phosphodiester bands; significant correlation coefficients are also observed for amide I and II bands.
Meurens, M., Wallon, J., Tong, J., Noël, H., & Haot, J. (1996). Breast cancer detection by Fourier transform infrared spectrometry. Vibrational Spectroscopy, 10(2), 341-346. https://doi.org/10.1016/0924-2031(95)00030-5 (Original work published 1996)