Accommodation and antibodies.

Dehoux, Jean-Paul;Gianello, Pierre
(2009) Transplant Immunology — Vol. 21, n° 2, p. 106-110 (2009)

Files

pdfdocument.pdf
  • Restricted Access
  • Adobe PDF
  • 162.4 KB
Dehouxtransplimmuno200921106.pdf
  • Restricted Access
  • Adobe PDF
  • 196.82 KB

Details

Authors
Abstract
Accommodation refers to the condition in which an organ transplant functions normally by acquiring resistance to immune-mediated injury (especially), despite the presence of anti-transplant antibodies in the recipient. This status is associated with several modifications in the recipient as well as in the graft, such as previous depletion of anti-graft antibodies and their slow return once the graft is placed; expression of several protective genes in the graft; a Th2 immune response in the recipient; and inhibition of the membrane attack complex of complement.
Affiliations

Citations

Dehoux, J.-P., & Gianello, P. (2009). Accommodation and antibodies. Transplant Immunology, 21(2), 106-110. https://doi.org/10.1016/j.trim.2008.10.002 (Original work published 2009)