Hepatic microsomal metabolism of 1,3-butadiene.
(1982) Xenobiotica : the fate of foreign compounds in biological systems — Vol. 12, n° 2, p. 137-144 (1982)
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- 1. In rat liver microsomes, 1,3-butadiene was metabolized to butadiene monoxide, which was subsequently transformed into 3-butene-1,2-diol by microsomal epoxide hydrolase. 2. In the metabolism of butadiene oxide in microsomes, four metabolites were detected, namely two stereoisomers of DL-diepoxybutane, and two stereoisomers of 3,4-epoxy-1,2-butanediol. No meso-diepoxybutane was detected.
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Malvoisin, E., & Roberfroid, M. (1982). Hepatic microsomal metabolism of 1,3-butadiene. Xenobiotica : the fate of foreign compounds in biological systems, 12(2), 137-144. https://hdl.handle.net/2078.5/55376 (Original work published 1982)