Screening and management of hypertensive patients with chronic kidney disease referred to Hypertension Excellence Centres among 27 countries. A pilot survey based on questionnaire.

Halimi, Jean-Michel;Sarafidis, Pantelis;Azizi, Michel;Bilo, Grzegorz;European Society of Hypertension Working Group on Hypertension, the Kidney;et.al.
(2024) Journal of Hypertension — Vol. 42, n° 9, p. 1544-1554 (2024)

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Authors
  • Halimi, Jean-Michel
    Author
  • Sarafidis, Pantelis
    Author
  • Azizi, Michel
    Author
  • Bilo, Grzegorz
    Author
  • Author
  • European Society of Hypertension Working Group on Hypertension, the Kidney
    Collaborator
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Abstract
OBJECTIVE: Real-life management of hypertensive patients with chronic kidney disease (CKD) is unclear. METHODS: A survey was conducted in 2023 by the European Society of Hypertension (ESH) to assess management of CKD patients referred to ESH-Hypertension Excellence Centres (ESH-ECs) at first referral visit. The questionnaire contained 64 questions with which ESH-ECs representatives were asked to estimate preexisting CKD management quality. RESULTS: Overall, 88 ESH-ECs from 27 countries participated (fully completed surveys: 66/88 [75.0%]). ESH-ECs reported that 28% (median, interquartile range: 15-50%) had preexisting CKD, with 10% of them (5-30%) previously referred to a nephrologist, while 30% (15-40%) had resistant hypertension. The reported rate of previous recent (<6 months) estimated glomerular filtration rate (eGFR) and urine albumin-creatinine ratio (UACR) testing were 80% (50-95%) and 30% (15-50%), respectively. The reported use of renin-angiotensin system blockers was 80% (70-90%). When a nephrologist was part of the ESH-EC teams the reported rates SGLT2 inhibitors (27.5% [20-40%] vs. 15% [10-25], P = 0.003), GLP1-RA (10% [10-20%] vs. 5% [5-10%], P = 0.003) and mineralocorticoid receptor antagonists (20% [10-30%] vs. 15% [10-20%], P = 0.05) use were greater as compared to ESH-ECs without nephrologist participation. The rate of reported resistant hypertension, recent eGFR and UACR results and management of CKD patients prior to referral varied widely across countries. CONCLUSIONS: Our estimation indicates deficits regarding CKD screening, use of nephroprotective drugs and referral to nephrologists before referral to ESH-ECs but results varied widely across countries. This information can be used to build specific programs to improve care in hypertensives with CKD.
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Citations

Halimi, J.-M., Sarafidis, P., Azizi, M., Bilo, G., Burkard, T., Bursztyn, M., Camafort, M., Chapman, N., Cottone, S., de Backer, T., Deinum, J., Delmotte, P., Dorobantu, M., Doumas, M., Dusing, R., Duly-Bouhanick, B., Fauvel, J.-P., Fesler, P., Gaciong, Z., et al. (2024). Screening and management of hypertensive patients with chronic kidney disease referred to Hypertension Excellence Centres among 27 countries. A pilot survey based on questionnaire. Journal of Hypertension, 42(9), 1544-1554. https://doi.org/10.1097/HJH.0000000000003756 (Original work published 2024)