Early Achromobacter xylosoxidans Endocarditis After the Valvular Mitral Replacement Complicated by an Agranulocytosis on B-lactams: A Case Report.

Channaoui, Aniss;Dubus, Michèle;Mathieu, Frédéric;Noirhomme, Séverine;Fontaine, Raphaël
(2023) Cureus — Vol. 15, n° 9, p. e46045 (2023)

Files

cureus-0015-00000046045.pdf
  • Open Access
  • Adobe PDF
  • 489.94 KB
Download

Details

Authors
  • Channaoui, Anissorcid-logoUCLouvain
    Author
  • Dubus, Michèle
    Author
  • Mathieu, Frédéric
    Author
  • Noirhomme, Séverine
    Author
  • Fontaine, Raphaël
    Author
Abstract
An immunocompetent 82-year-old woman developed endocarditis caused by an atypical organism called Achromobacter xylosoxidans, after a first valvular surgery. The intravenous antibiotic therapy with ceftazidime - 2 g every 8 hours during five weeks - a key part of the treatment, induced agranulocytosis as an adverse event. Cross-reactivity between antibiotics was suspected. Finally, the patient's cure was the result of a coordinated effort between medical and surgical professionals. Postoperative follow-up is six years.
Affiliations

Citations

  • APA
  • Chicago
  • FWB

Channaoui, A., Dubus, M., Mathieu, F., Noirhomme, S., & Fontaine, R. (2023). Early Achromobacter xylosoxidans Endocarditis After the Valvular Mitral Replacement Complicated by an Agranulocytosis on B-lactams: A Case Report. Cureus, 15(9), e46045. https://doi.org/10.7759/cureus.46045 (Original work published 2023)