Compared with medialization laryngoplasty, injection laryngoplasty offers the advantages of being easy to perform, noninvasive, and readily repeated. For correcting the lamina propria, the authors prefer medial injection techniques, ie, in the deep layer of the lamina propria, to medialization laryngoplasty, because medialization laryngoplasty merely approximates the vocal folds. For vocal fold scars and sulcus vergeture lesions, the injection is preceded by raising a microflap to free the adherent area. The suitability of injection laryngoplasty versus medialization laryngoplasty is open to discussion for glottic gaps caused by immobility in a paramedian or intermediate position or resulting from presbyphonia. Medialization laryngoplasty is indicated for glottic immobility in a lateral position. Injection techniques are merely complementary procedures when postmedialization results remain insufficient. We recommend medialization laryngoplasty for extended posttraumatic vocal fold scars or scarring after endoscopic cordectomy. Whereas autologous fat requires a lateral injection, we advocate the deep layer of the lamina propria as the preferred injection site for materials that are natural constituents of Reinke space (GAX-collagen, homologous collagens, and possibly hyaluronic acid). These materials require a smaller injection dose, and resorption is much slower in Reinke space than in muscle.
Remacle, M., & Lawson, G. (2001). Injectable substances for vocal fold augmentation. Current Opinion in Otolaryngology & Head and Neck Surgery, 9, 393-397. https://hdl.handle.net/2078.5/96975 (Original work published 2001)