To the Editor, From a historical perspective, significant efforts were made to identify the cell types responsible for collagen production in the liver during fibrosis. Kupffer discovered stellate cells in 1876. In 1952, Ito and Nemoto observed prominent lipid droplets in cells located around the liver sinusoids and termed them fat-storing cells. [...]
Ezhilarasan, D., & Najimi, M. (2024). Quiescent hepatic stellate cell activation in liver fibrosis: Have we found the right trigger yet? Clinics and Research in Hepatology and Gastroenterology, 48(7), 102420 [1-2]. https://doi.org/10.1016/j.clinre.2024.102420 (Original work published 2024)