(en) Pathological left ventricular remodeling following myocardial infarction (MI) is a major contributor to the development of heart failure. This process is primarily characterized by a sterile inflammatory response and subsequent fibrosis in the myocardium, involving a complex interplay of cellular and molecular actors. In this journal, Vinhais da Silva et al. delve into the intricate and underexplored role of P2 purinergic receptors in cardiac healing post-MI. [...]
Dufeys, C., Bertrand, L., Beauloye, C., & Horman, S. (2025). P2 purinergic receptors: A key but underexplored player in post-myocardial infarction healing. American journal of physiology. Heart and circulatory physiology, 329(2), H457-H458. https://doi.org/10.1152/ajpheart.00179.2025 (Original work published 2025)