Vocal fold augmentation with calcium hydroxylapatite (CaHA)
(2007) Otolaryngology - Head and Neck Surgery — Vol. 136, n° 2, p. 198-204 (2007)
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- OBJECTIVES: Evaluate the effectiveness of CaHA injection for patients with glottal incompetence. METHODS: Multi-center, open-label, prospective clinical study with each patient serving as his/her own control. Voice-related outcome measures were collected for pre-injection and 1, 3, and 6 months. RESULTS: Sixty-eight patients were available for evaluation. Fifty percent of the injection procedures were done in office. Fifty-seven percent were diagnosed with unilateral paralysis and 42% with glottal incompetence with mobile vocal folds. Patient satisfaction 6 months post showed 56% had significantly improved voice and 38% reported moderately improved voice. Paired t tests from baseline to 6 months showed significant improvements on the VHI and VAS (vocal effort), CAPE-V judgments of voice severity and videoendostroboscopy ratings of glottal closure, and objective voice measures of glottal closure (MPT and S:Z ratio). CONCLUSIONS: Preliminary results in this large cohort of patients demonstrate excellent clinical results. (C) 2007 American Academy of Otolarynaology-Head and Neck Surgery Foundation. All rights reserved.
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Rosen, C. A., Gartner-Schmidt, J., Casiano, R., Anderson, T. D., Johnson, F., Reussner, L., Remacle, M., Sataloff, R. T., Abitbol, J., Shaw, G., Archer, S., & McWhorter, A. (2007). Vocal fold augmentation with calcium hydroxylapatite (CaHA). Otolaryngology - Head and Neck Surgery, 136(2), 198-204. https://doi.org/10.1016/j.otohns.2006.07.014 (Original work published 2007)