Nephrotoxic effects of thermal decomposition mixtures of type C hydraulic fluids.
(1994) Toxicology and Industrial Health : an international journal — Vol. 10, n° 3, p. 143-147 (1994)
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- Abstract
- A survey was conducted to check the toxicological impact of ethylene glycol present in a thermal decomposition mixture of type C hydraulic fluid on laboratory animals submitted to an inhalation test. The target organs, i.e. kidneys, of exposed rats were evaluated histologically and oxalic acid--the ethylene glycol metabolite thought to cause renal failure--was quantified in urine samples. The results show that the low ethylene glycol concentrations present in the inhalation chamber produce only a temporarily increased oxalic acid excretion, at levels that are not significant. These findings are supported by the histological evaluation of the kidneys showing no calcium oxalate deposits or other abnormalities.
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Van Damme, J., Verbeken, E. K., & Daenens, P. J. (1994). Nephrotoxic effects of thermal decomposition mixtures of type C hydraulic fluids. Toxicology and Industrial Health : an international journal, 10(3), 143-147. https://hdl.handle.net/2078.5/71486 (Original work published 1994)