Evaluation of MP4OX for prevention of perioperative hypotension in patients undergoing primary hip arthroplasty with spinal anesthesia: a randomized, double-blind, multicenter study.
(2011) Anesthesiology — Vol. 114, n° 5, p. 1048-1063 (2011)
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- Abstract
- MP4OX (oxygenated polyethylene glycol-modified hemoglobin) is an oxygen therapeutic agent with potential applications in clinical settings where targeted delivery of oxygen to ischemic tissues is required. The primary goal of this study was to investigate MP4OX for preventing hypotensive episodes. An additional goal was to establish the safety profile of MP4OX in a large surgical population.
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Olofsson, C. I., Górecki, A. Z., Dirksen, R., Kofranek, I., Majewski, J. A., Mazurkiewicz, T., Jahoda, D., Fagrell, B., Keipert, P. E., Hardiman, Y. J., & Levy, H. (2011). Evaluation of MP4OX for prevention of perioperative hypotension in patients undergoing primary hip arthroplasty with spinal anesthesia: a randomized, double-blind, multicenter study. Anesthesiology, 114(5), 1048-1063. https://hdl.handle.net/2078.5/190771 (Original work published 2011)