Amplification of epidermal growth factor receptor gene in renal cell carcinoma
(2010) European Journal of Cancer — Vol. 46, n° 5, p. 859-862 (2010)
Files
pdfdocument.pdf
Restricted Access - Adobe PDF
- 135.71 KB
Details
- Authors
- Abstract
- Expression of epidermal growth factor receptor (EGER) may be of prognostic value in renal cell cancer (RCC). Gene amplification of EGER was investigated in a cohort of 315 patients with advanced RCC from a previously reported randomised study. Using fluorescent in situ hybridisation, only 2 patients (0.6%) had gene amplification; therefore gene amplification is of no prognostic value in RCC.
- Affiliations
Citations
El-Hariry, I., Powles, T., Lau, M. R., Sternberg, C. N., Ravaud, A., von der Maase, H., Zantl, N., Harper, P., Rolland, F., Audhuy, B., Barthel, F., Machiels, J.-P., Patel, P., Kreuser, E.-D., & Hawkins, R. E. (2010). Amplification of epidermal growth factor receptor gene in renal cell carcinoma. European Journal of Cancer, 46(5), 859-862. https://doi.org/10.1016/j.ejca.2010.01.011 (Original work published 2010)