An adequate initial antibiotic therapy is a key determinant of therapeutic success in Pseudomonas aeruginosa - infected patients. Antibiotic effl ux is an underestimated resistance mechanism because it may occur in strains categorized as susceptible. It is rarely or not at all diagnosed in routine laboratories and often masked by high-level resistance mechanisms
Avrain, L., Mertens, P., & Van Bambeke, F. (2013). RND efflux pumps in P. aeruginosa: an underestimated resistance mechanism. Clinical Laboratory International, April-May, 26. https://hdl.handle.net/2078.5/202123 (Original work published 2013)