The measurement of DLNO and DLCO: A manufacturer's perspective.

Giraud, Xavier;Le-Dong, Nhât Nam;Hogben, Kevin;Martinot, Jean-Benoît
(2017) Respiratory Physiology & Neurobiology — Vol. 241, p. 36-44 (2017)

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Authors
  • Giraud, Xavier
    Author
  • Le-Dong, Nhât Nam
    Author
  • Hogben, Kevin
    Author
  • Martinot, Jean-BenoîtUCLouvain
    Author
Abstract
The simultaneous measurement of the lung transfer factor for carbon monoxide (DLCO) and nitric oxide (DLNO) is now available as a powerful method for studying the alveolar-capillary gas exchange. However, application of the DLNO-CO technique in daily settings is still limited by some technical drawbacks. This paper provides a manufacturer's overview of the measuring principles, technical challenges and current available solutions for implementing the DLNO-CO measurement in to a marketed device. This includes the recent developments in technology for NO sensors, latest findings on NO uptake and new statistical methods.
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Giraud, X., Le-Dong, N. N., Hogben, K., & Martinot, J.-B. (2017). The measurement of DLNO and DLCO: A manufacturer’s perspective. Respiratory Physiology & Neurobiology, 241, 36-44. https://doi.org/10.1016/j.resp.2017.02.006 (Original work published 2017)