Joint and entheseal inflammation in the knee region in spondyloarthritis - reliability and responsiveness of two OMERACT whole-body MRI scores.
(2021) Seminars in Arthritis and Rheumatism — Vol. 51, n° 4, p. 933-939 (2021)
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- (en) OBJECTIVE: To perform region-based development of whole-body MRI through validation of knee region scoring systems in spondyloarthritis (SpA). METHODS: Assessment of knee inflammatory pathologies using 2 systems, OMERACT MRI Whole-body score for Inflammation in Peripheral joints and Entheses (MRI-WIPE) and Knee Inflammation MRI Scoring System (KIMRISS), in 4 iterative multi-reader exercises. RESULTS: In the final exercise, reliability was mostly good for readers with highest agreement in previous exercise. Median pairwise single-measure ICCs for osteitis and synovitis/effusion status/change were 0.71/0.48 (WIPE-osteitis), 0.48/0.77 (WIPE-synovitis/effusion), 0.59/0.91 (KIMRISS-osteitis) and 0.92/0.97 (KIMRISS-synovitis/effusion). SRMs were 0.74 (WIPE-synovitis/effusion) and 0.78 (KIMRISS-synovitis/effusion). CONCLUSION: MRI-WIPE and KIMRISS may both be useful in SpA whole-body evaluation studies.
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Wetterslev, M., Maksymowych, W. P., Lambert, R. G., Eshed, I., Pedersen, S. J., Stoenoiu, M., Krabbe, S., Bird, P., Foltz, V., Mathew, A. J., Gandjbakhch, F., Paschke, J., Carron, P., De Marco, G., Marzo-Ortega, H., Poulsen, A. E., Jaremko, J. L., Conaghan, P. G., & Østergaard, M. (2021). Joint and entheseal inflammation in the knee region in spondyloarthritis - reliability and responsiveness of two OMERACT whole-body MRI scores. Seminars in Arthritis and Rheumatism, 51(4), 933-939. https://doi.org/10.1016/j.semarthrit.2021.05.013 (Original work published 2021)