A 76-year-old man was diagnosed with a hematological neoplasm combining myelodysplastic and myeloproliferative characteristics back in July 2021. Five months after the diagnosis, his condition got more severe when the blasts rose up to 14%, so he was started on hypomethylating agent-based therapy. A few weeks later, the patient was hospitalized after developing fever and a pain in the right thigh. To exclude any source of occult infection, an 18 F-FDG PET/CT was performed. FDG PET/CT showed a complete lack of metabolism in the right femur. An MRI and a biopsy confirmed the suspected diagnosis of osteonecrosis.
Kargar Samani, I., Akachar, Y., & Krug, B. (2023). Complete Femoral Osteonecrosis in the Setting of Myelodysplastic Syndrome. Clinical Nuclear Medicine, 48(3), 242-244. https://doi.org/10.1097/RLU.0000000000004507 (Original work published 2023)