Automated extraction of nested sulcus features from human brain MRI data

Bao, Forrest;Giard, Joachim;Tourville, Jason;Klein, Arno
(2012) Engineering in Medicine and Biology Society (EMBC), 2012 Annual International Conference of the IEEE

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Authors
  • Bao, ForrestTexas Tech University
    Author
  • Giard, JoachimUCLouvain
    Author
  • Tourville, JasonBoston University
    Author
  • Klein, ArnoColumbia University
    Author
Abstract
Extracting objects related to a fold in the cerebral cortex (“sulcus features”) from human brain magnetic resonance imaging data has applications in morphometry, landmark-based registration, and anatomical labeling. In prior work, sulcus features such as surfaces, fundi and pits have been extracted separately. Here we define and extract nested sulcus features in a hierarchical manner from a cortical surface mesh having curvature or depth values. Our experimental results show that the nested features are comparable to features extracted separately using other methods, and that they are consistent across subjects and with manual label boundaries. Our open source feature extraction software will be made freely available as part of the Mindboggle project (http://www.mindboggle.info).
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Bao, F., Giard, J., Tourville, J., & Klein, A. (2012). Automated extraction of nested sulcus features from human brain MRI data. Engineering in Medicine and Biology Society (EMBC), 2012 Annual International Conference of the IEEE, 4429-4433. https://doi.org/10.1109/EMBC.2012.6346949 (Original work published 2012)