The role of artificial intelligence in the clinical laboratory: challenges and opportunities. Highlights from the artificial intelligence in the Clinical Laboratory Session at the 56th SIBioC Congress, 2024

Carobene, Anna;Gruson, Damien;Cadamuro, Janne;Cabitza, Federico;Padoan, Andrea;et.al.
(2025) Biochimica Clinica — Vol. 49, n° 2, p. 144-153 (2025)

Files

2025_Carobene_Biochimica_Clinica_AB.pdf
  • Open Access
  • Adobe PDF
  • 361.56 KB
Download

Details

Authors
  • Carobene, Anna
    Author
  • Gruson, DamienUCLouvain
    Author
  • Cadamuro, Janne
    Author
  • Cabitza, Federico
    Author
  • Padoan, Andrea
    Author
Show more
Abstract
(en) Artificial intelligence (AI) is revolutionizing laboratory medicine (LM), offering opportunities to enhance diagnostics, optimize workflows and services, and improve patient outcomes. AI’s ability to analyze complex datasets holds great potential in LM, where vast amounts of data are processed. Key applications include hyper-automation, personalized medicine, and augmented diagnostics. However, AI integration may face challenges such as data security, algorithmic bias, and potential concerns about dehumanizing care. A European survey revealed gaps in AI adoption, with many laboratories lacking the necessary infrastructure and structured data for implementation. High-quality, interoperable data is essential for practical deployment. At the 56th Italian Society of Clinical Biochemistry-Laboratory Medicine (SIBioC) Congress (Bologna, October 2024), experts explored these opportunities and challenges. The session emphasized the need for explainable AI to build model reliability and clinician trust. A key point in the discussion was the robustness of AI models, which is crucial for their successful application. Comprehensive validation processes, including external validation, are required to ensure consistent performance across diverse clinical settings. AI’s potential to transform sepsis screening through machine learning models using parameters like monocyte distribution width (MDW) was demonstrated, with promising results in early detection. This project, led by the SIBioC Working Group, highlighted the importance of rigorous validation. However, real-world implementation of AI demands infrastructure development, educational efforts, and regulatory frameworks. Scientific societies like SIBioC play a crucial role in fostering interdisciplinary collaboration to promote the responsible adoption of AI in LM. The session concluded that while AI holds great promise, its success depends on addressing ethical, technological, and practical challenges.
Affiliations

Citations

  • APA
  • Chicago
  • FWB

Carobene, A., Gruson, D., Cadamuro, J., Cabitza, F., Agnello, L., Campagner, A., & Padoan, A. (2025). The role of artificial intelligence in the clinical laboratory: challenges and opportunities. Highlights from the artificial intelligence in the Clinical Laboratory Session at the 56th SIBioC Congress, 2024. Biochimica Clinica, 49(2), 144-153. https://doi.org/10.23736/S0393-0564.24.00007-0 (Original work published 2025)