DEAR EDITOR, The thorough meta-analysis by Palawaththa et al. on congenital anomalies and maternal niacin intake, provides important prevention opportunities. Their statement, however, that synthesis of NAD+ from tryptophan also requires dietary niacin may confuse readers [...].
Vermorken, A. J. M., Zhu, J., Ma, L., & Cui, Y. (2023). Can niacin supplementation prevent congenital malformations associated with maternal use of proton pump inhibitors? European Journal of Nutrition, 62(2), 1051-1053. https://doi.org/10.1007/s00394-022-03060-1 (Original work published 2023)