[Ca2+]c in single mouse α-cells is controlled by modulators of K+ATP channels but not by glucose
(2006) Belgian Society for Fundamental and Clinical Physiology and Pharmacology, Spring Meeting 2006 — Location: (Belgium) Bruxelles (5.June.2006)
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- BACKGROUND AND AIMS: Stimulus-secretion coupling in pancreatic α-cells is poorly understood. Changes in the free cytosolic Ca2+ concentration ([Ca2+]c) are implicated in the control of glucagon release, but the mechanisms by which secretagogues modify α-cell [Ca2+]c remain highly controversial. These were studied here in single α-cells isolated from a mouse model expressing a fluorescent protein (FP) under the control of the glucagon promoter. [...[
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Quoix, N., Mattart, L., Zeinoun, Z., Beauvois, M. C., Henquin, J.-C., & Gilon, P. (2006). [Ca2+]c in single mouse α-cells is controlled by modulators of K+ATP channels but not by glucose. Acta Physiologica, 187(Suppl 652), P09. https://hdl.handle.net/2078.5/119040 (Original work published 2006)