Genes coding for melanoma antigens recognised by cytolytic T lymphocytes

De Smet, Charles;Lurquin, Christophe;De Plaen, Etienne;Brasseur, Francis;Boon-Falleur, Thierry;et.al.
(1997) Eye — Vol. 11, p. 243-248 (1997)

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Authors
  • Author
  • Lurquin, Christophe
    Author
  • De Plaen, EtienneUCLouvain
    Author
  • Brasseur, FrancisUCLouvain
    Author
  • Author
  • Boon-Falleur, ThierryUCLouvain
    Author
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Abstract
It is now well established that human melanoma cells express antigens that are recognised by cytolytic T lymphocytes derived from the tumour-bearing patient. The molecular definition of these antigens is progressing at an accelerated pace. The currently characterised melanoma antigens can be classified into three categories: differentiation antigens, antigens encoded by genes that are specifically expressed in tumours, and antigens encoded by mutated genes. Several of these antigens are sufficiently tumour-specific to qualify them as candidate anti-cancer vaccines in melanoma patients.
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Citations

De Smet, C., Lurquin, C., De Plaen, E., Brasseur, F., Zarour, H., De Backer, O., Coulie, P., & Boon-Falleur, T. (1997). Genes coding for melanoma antigens recognised by cytolytic T lymphocytes. Eye, 11, 243-248. https://doi.org/10.1038/eye.1997.59 (Original work published 1997)