Etude de la microalbuminurie dans une population de 653 patients diabétiques de type 1 et 2.

Descamps, O.;Buysschaert, Martin;Ketelslegers, Jean-Marie;Hermans, Michel;Lambert, A E
(1991) Diabete et Metabolisme — Vol. 17, n° 5, p. 469-475 (1991)

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Authors
  • Descamps, O.
    Author
  • Buysschaert, MartinUCLouvain
    Author
  • Ketelslegers, Jean-MarieUCLouvain
    Author
  • Hermans, MichelUCLouvain
    Author
  • Lambert, A E
    Author
Abstract
The aim of this retrospective study was to evaluate the prevalence of microalbuminuria in type 1 and 2 diabetic patients with or without high blood pressure levels. 653 patients were involved in the study [type 1: n = 413 (normotensive: n = 298; hypertensive: n = 115); type 2: n = 240 (normotensive: n = 93; hypertensive: n = 147)]. In type 1 diabetic patients, the prevalence of microalbuminuria was of 21 per cent. Microalbuminuria was also found in 28 per cent of type 2 diabetic subjects (p less than 0.10 vs type 1). The prevalence of microalbuminuria was significantly higher in hypertensive than in normotensive diabetic subjects (28 vs 20 per cent; p less than 0.05). Blood pressure in type 1 and 2 normotensive patients was significantly higher in subjects with than without microalbuminuria. We also observed higher HbA1 levels in microalbuminuric type 1 diabetic patients. Finally, we also assessed that the prevalence of diabetic chronic complications was higher in type 1 patients with than without microalbuminuria (p less than 0.05). This relationship was not evidenced in type 2 diabetic patients. In conclusion, the prevalence of microalbuminuria in a population of type 1 and 2 diabetic patients is high. We confirm in this study the relationship between microalbuminuria, blood pressure, and HbA1.
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Descamps, O., Buysschaert, M., Ketelslegers, J.-M., Hermans, M., & Lambert, A. E. (1991). Etude de la microalbuminurie dans une population de 653 patients diabétiques de type 1 et 2. Diabete et Metabolisme, 17(5), 469-475. https://hdl.handle.net/2078.5/83519 (Original work published 1991)