(en) α-hederin is a triterpenoid saponin which has shown hemolytic and apoptotic properties. (Chwalek et al. 2006, Gauthier et al. 2009). Many saponins are known to interact with biological membranes on a cholesterol dependent or independent manner (Francis et al. 2002) but the underlying mechanisms need to be further explored. [...]
Lorent, J., Quetin-Leclercq, J., & Mingeot-Leclercq, M.-P. (2012). The action of alpha-hederin, a triterpenoid saponin on membranes. Biophysical Journal, 102(3), 85a. https://hdl.handle.net/2078.5/179188 (Original work published 2012)