Paraneoplastic limbic encephalitis: diagnostic relevance of CSF analysis and total body PET scanning.
(2004) Acta Neurologica Belgica — Vol. 104, n° 2, p. 57-63 (2004)
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- Abstract
- We report two cases of paraneoplastic limbic encephalitis (PLE) that differed in their clinical patterns, the underlying tumours, and the associated paraneoplastic antibodies. The first patient was a young adult male, with anti-MA-2 antibodies and testicular tumour. The clinical picture was restricted to limbic involvement. The second patient was a 56-year old, female heavy smoker; with seizures and depression, but also vertigo and diplopia. A low level of serum anti-Hu antibodies led to the detection of a small cell lung carcinoma by total body PET-scanning. In both cases, intrathecal synthesis of CSF oligoclonal IgG bands and of the corresponding paraneoplastic antibodies was demonstrated.
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Citations
Dreessen, J., Jeanjean, A., & Sindic, C. (2004). Paraneoplastic limbic encephalitis: diagnostic relevance of CSF analysis and total body PET scanning. Acta Neurologica Belgica, 104(2), 57-63. https://hdl.handle.net/2078.5/132380 (Original work published 2004)