Pancreas Transplantation at the University of Louvain : Results of 2 successive techniques
(1991) Zeitschrift fuer Transplantationsmedizin — Vol. 3, p. S86-S89 (1991)
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- Abstract
- Today, combined kidney and pancreas transplantation is the best treatment for patients with type I diabetes and pre-end or end-stage renal disease due to the diabetic nephropathy. Thirty three patients (35 pancreases, 33 kidneys and 1/iver) underwent thatprocedure at our Institution (2 patients received 2 pancreases). Recent technical modifications - with the use of a whole pancreas graft with urinary drainage of the exocrine secretion in the recipient by peJforming a pancreaticoduodenocystostomy - allow the monitoring of the exocrine secretion which is a pertinent immunological marker for pancreas rejection. Current actuarial survival rates for patients, kidneys and pancreases are respective/y 87%, 81% and 77% at one year. In the next future, pancreas a/one should be consideree! safely using the same procedure, in non uremie diabetic recipients in whom extra-renal secondary complications are more serious than the potential side effects of chronic immunosuppression. That type of pancreas transplantation should benefit of the forthcoming immunosuppressive drugs.
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Citations
Squifflet, J.-P., Vandeleene, B., Gianello, P., Pirson, Y., & Alexandre, G. P. J. (1991). Pancreas Transplantation at the University of Louvain : Results of 2 successive techniques. Zeitschrift fuer Transplantationsmedizin, 3, S86-S89. https://hdl.handle.net/2078.5/64377 (Original work published 1991)