An Anatomoclinical Study of Delayed Skin Allergic Reactions To Nickel Following Intradermal Injections of Lidocaine With a Dermo-jet

Lachapelle, Jean-Marie;Tennstedt, Dominique
(1982) Contact Dermatitis : environmental and occupational dermatitis — Vol. 8, n° 3, p. 193-199 (1982)

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  • Lachapelle, Jean-MarieUCLouvain
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  • Tennstedt, Dominique
    Author
Abstract
10 women allergic in nickel developed skin reactions al injection sites with a Dermo-Jet (Krantz® model) of (a) 2% lidocaïne solution and (b)0.9% Saline solution. 10 women (age-matched) not allergic to nickel were selected as controls and submitted to the same injections; they had no positive reactions. Various controls (including injections with a needle and patch tests) were made in both groups. Nickel was leached into fluids from the metallic internal parts of the Dermo-Jet. The positive reactions were allergic and due to nickel. Histology showed changes of an allergic contact dermatitis with particular features, probably due to the intradermal injection of nickel. Some practical implications regarding the quality of medical instruments are discussed
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Lachapelle, J.-M., & Tennstedt, D. (1982). An Anatomoclinical Study of Delayed Skin Allergic Reactions To Nickel Following Intradermal Injections of Lidocaine With a Dermo-jet. Contact Dermatitis : environmental and occupational dermatitis, 8(3), 193-199. https://doi.org/10.1111/j.1600-0536.1982.tb04182.x (Original work published 1982)