Contrôle hormonal de la gluconéogénèse hépatique.

Hue, Louis
(1982) Revue Canadienne de Biologie et Biologie Experimentale — Vol. 41, n° 1, p. 73-76 (1982)

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  • Hue, LouisUCLouvain
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Abstract
The stimulation of gluconeogenesis by glucagon results from a concerted mechanism involving: 1) the stimulation of pyruvate transport and carboxylation in mitochondria; 2) the cyclic AMP dependent phosphorylation and inactivation of pyruvate kinase resulting in a re-routing of phosphoenolpyruvate towards glucose; 3) the inhibition of phosphofructokinase and the stimulation of fructose bisphosphatase resulting from the disappearance of fructose-2,6-bisphosphate. Catecholamines and vasopressin stimulate gluconeogenesis in starvation whereas in the fed state they promote glycogenolysis together with glycolysis.
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Hue, L. (1982). Contrôle hormonal de la gluconéogénèse hépatique. Revue Canadienne de Biologie et Biologie Experimentale, 41(1), 73-76. https://hdl.handle.net/2078.5/84619 (Original work published 1982)