(en) The progression of alcohol-associated liver disease (ALD) in its early precirrhotic stages can be a silent process. Serum keratin 18 levels (K18-M65) predict severe events and mortality in advanced stages of ALD, but data on this biomarker in early stages are scarce. We evaluated the diagnostic accuracy of K18-M65 levels in identifying early forms of ALD.
Maccioni, L., Horsmans, Y., Leclercq, I., Schnabl, B., & Stärkel, P. (2023). Serum keratin <scp>18‐M65</scp> levels detect progressive forms of alcohol‐associated liver disease in early noncirrhotic stages. Alcoholism: Clinical and Experimental Research, 47(6), 1079-1087. https://doi.org/10.1111/acer.15081 (Original work published 2023)