Bone marrow transplantation from an unrelated donor for Fanconi's anaemia: two unusual complications.

Sokal, Etienne;Michel, Marcel;Ninane, J.;Latinne, Dominique;Cornu, Guy;et.al.
(1987) Bone Marrow Transplantation — Vol. 2, n° 1, p. 99-102 (1987)

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Authors
  • Sokal, EtienneUCLouvain
    Author
  • Michel, MarcelUCLouvain
    Author
  • Ninane, J.
    Author
  • Latinne, DominiqueUCLouvain
    Author
  • De Bruyère, MarcUCLouvain
    Author
  • Cornu, GuyUCLouvain
    Author
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Abstract
An eight-year-old boy with Fanconi's anaemia received a bone marrow transplantation from an unrelated donor. Sustained engraftment was achieved, but he developed major complications including acute grade III graft-versus-host disease, autoimmune haemolytic anaemia with positive Coombs' test and free antibodies against Rhesus group, and a virus-associated haemophagocytic syndrome; this latter complication was successfully treated with acyclovir. Sixteen months after transplantation he has full haematopoietic reconstitution, but with persisting mild autoimmune haemolysis.
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Citations

Sokal, E., Michel, M., Ninane, J., Latinne, D., De Bruyère, M., & Cornu, G. (1987). Bone marrow transplantation from an unrelated donor for Fanconi’s anaemia: two unusual complications. Bone Marrow Transplantation, 2(1), 99-102. https://hdl.handle.net/2078.5/53292 (Original work published 1987)