F-18 FDG PET/CT as a noninvasive diagnostic and follow-up tool in brown tumors due to secondary hyperparathyroidism

Hermoye, Aurélie;Malghem, Jacques;Lecouvet, Frédéric;Goffin, Eric;Lhommel, Renaud;et.al.
(2009) Clinical Nuclear Medicine — Vol. 34, n° 5, p. 330-332 (2009)

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Abstract
We report the case of a 47-year-old woman, who had hemodialysis with secondary hyperparathyroidism and who developed progressive unbearable leg pain. Bone lesions suggestive of brown tumors were observed on initial x-ray examinations. This etiology was strengthened by PET/CT images showing F-18 FDG avid osteolytic lesions but no abnormal uptake suggestive of a primary neoplasm. The major metabolic regression of the lesions 6 months after total parathyroidectomy eventually confirmed the diagnosis. This case illustrates the potential usefulness of PET/CT in the noninvasive diagnosis and follow-up of brown tumors.
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Hermoye, A., Malghem, J., Lecouvet, F., Goffin, E., Lonneux, M., & Lhommel, R. (2009). F-18 FDG PET/CT as a noninvasive diagnostic and follow-up tool in brown tumors due to secondary hyperparathyroidism. Clinical Nuclear Medicine, 34(5), 330-332. https://doi.org/10.1097/RLU.0b013e31819e52a9 (Original work published 2009)