MDA5 Dermatomyositis Is Associated with Stronger Skin Type I Interferon Transcriptomic Signature with Upregulation of IFN-κ Transcript.
(2020) The Journal of Investigative Dermatology — Vol. 140, n° 6, p. 1276-1279 (2020)
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- (en) TO THE EDITOR, Dermatomyositis (DM) is a chronic inflammatory and autoimmune disorder belonging to the idiopathic inflammatory myopathies affecting primarily skin and muscle with variable extent. Disease mechanism comprehension is growing, with a pivotal role of both the innate and adaptive immune system and involvement of both cellular and humoral actors (Nagaraju and Lundberg, 2011). [...]
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Cassius, C., Amode, R., Delord, M., Battistella, M., Poirot, J., How-Kit, A., Lepelletier, C., Jachiet, M., de Masson, A., Frumholtz, L., Cordoliani, F., Boccara, D., Lehmann-Che, J., Wong, J., Dubanchet, S., Alberdi, A. J., Merandet, M., Bagot, M., Bensussan, A., et al. (2020). MDA5 Dermatomyositis Is Associated with Stronger Skin Type I Interferon Transcriptomic Signature with Upregulation of IFN-κ Transcript. The Journal of Investigative Dermatology, 140(6), 1276-1279. https://doi.org/10.1016/j.jid.2019.10.020 (Original work published 2020)