Regional brain glucose metabolism was studied in a case of postischaemic thalamic syndrome. Despite a normal density of the thalamus on MRI and CT images, a 17% relative hypometabolism was found in the posterior thalamus on the affected side. This observation of functional anomalies in the posterior thalamic complex in case of thalamic syndrome is compatible with a deregulated processing of pain-related information at this level.
Laterre, E.-C., De Volder, A., & Goffinet, A. (1988). Brain glucose metabolism in thalamic syndrome. Journal of neurology, neurosurgery, and psychiatry, 51(3), 427-428. https://doi.org/10.1136/jnnp.51.3.427 (Original work published 1988)