Human fascioliasis: cure by mebendazole? A case report.

Dugernier, T.;Geubel, André;Bigaignon, Geoffroy;Cesbron, J Y;Coche, Edgard
(1986) Gastroenterologie Clinique et Biologique — Vol. 10, n° 6-7, p. 513-516 (1986)

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Authors
  • Dugernier, T.
    Author
  • Geubel, AndréUCLouvain
    Author
  • Bigaignon, GeoffroyUCLouvain
    Author
  • Cesbron, J Y
    Author
  • Coche, EdgardUCLouvain
    Author
Abstract
We report a case of invasive human Fasciola hepatica infection in which, for the first time, a successful treatment with high doses of mebendazole (4 g/day for 3 weeks) was achieved. This therapy resulted in a prompt and prolonged normalization of eosinophil counts, liver enzymes abnormalities and specific serological tests together with the disappearance of liver necrosis indicating the eradication of liver flukes. The efficacy of mebendazole in the treatment of fascioliasis must be confirmed by further studies.
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Dugernier, T., Geubel, A., Bigaignon, G., Cesbron, J. Y., & Coche, E. (1986). Human fascioliasis: cure by mebendazole? A case report. Gastroenterologie Clinique et Biologique, 10(6-7), 513-516. https://hdl.handle.net/2078.5/128112 (Original work published 1986)