Non-invasive ventilation: Evaluation of CO<inf>2</inf> washout by intentional leaking in three recent oronasal masks. A pilot study

Médrinal, Clément;Prieur, Guillaume;Contal, Olivier;Villiot-Danger, Estelle;Quieffin, Jean;et.al.
(2015) Minerva Anestesiologica : a journal on anesthesiology, resuscitation, analgesia and intensive care — Vol. 81, n° 5, p. 526-532 (2015)

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Authors
  • Médrinal, Clément
    Author
  • Prieur, Guillaume
    Author
  • Contal, Olivier
    Author
  • Villiot-Danger, Estelle
    Author
  • Reychler, Gregoryorcid-logoUCLouvain
    Author
  • Quieffin, Jean
    Author
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Abstract
Background. Many types of interfaces with intentional leaks exist for Non Invasive Ventilation. The purpose of intentional leaks is to remove CO<inf>2</inf> from the interface, however the calibration does not allow a sufficiently large flow and rebreathing of CO<inf>2</inf> can occur. The aim of this study was to compare the CO<inf>2</inf> rinsing capacities of three new generation oronasal masks with intentional leaks (A: Quattro®, [Resmed]; B: Amara® [Respironics]; C: Forma® [Fisher&Paykel]) in healthy subjects. Methods. Seventeen healthy volunteers were included in this prospective cross-sectional, randomized, double-blinded trial. Each subject underwent ventilation with a home ventilator (IPAP: 14 cmH<inf>2</inf>O; EPAP: 4 cmH<inf>2</inf>O) with each mask consecutively. Transcutaneous capnography (PtcCO<inf>2</inf>) recordings were carried out throughout the trial and ventilator data (tidal volume, respiratory rate, minute ventilation and unintentional leaks) were also analyzed. Mask comfort was assessed using a visual analog scale (0 to 10). Results. The results showed no differences in PtcCO<inf>2</inf> between masks (P=0.82). There were no significant differences in respiratory parameters (tidal volume, P=0.79; respiratory rate, P=0.65; minute ventilation, P=0.12) between masks. The rate of unintentional leaks were significantly lower for Mask A (P=0.016). Subjects rated Mask A and Mask C as more comfortable than Mask B (P=0.041). Conclusion. There was no effect of mask on PtcCO<inf>2</inf> in healthy subjects. The mask with the highest comfort rating had not the lowest rate of unintentional leaks.
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Médrinal, C., Prieur, G., Contal, O., Villiot-Danger, E., Doyle, C., Reychler, G., & Quieffin, J. (2015). Non-invasive ventilation: Evaluation of CO<inf>2</inf> washout by intentional leaking in three recent oronasal masks. A pilot study. Minerva Anestesiologica : a journal on anesthesiology, resuscitation, analgesia and intensive care, 81(5), 526-532. https://hdl.handle.net/2078.5/212731 (Original work published 2015)