Although alcohol dependency is a burden to society, data on cognitive performance in therapy-resistant patients after multiple withdrawals are poor. In this study, 22 patients without reported cognitive deficits and 20 control subjects performed extensive cognitive testing and a motor task assessing short-term memory. Patients displayed subtle deficits (mainly in executive function), while memory functions were relatively unimpaired. Our results suggest that subtle frontal-executive deficits may contribute to a poor prognosis, but could be missed by routine clinical tests.
Wollenweber, F. A., Halfter, S., Brügmann, E., Weinberg, C., Cieslik, E. C., Müller, V. I., Hardwick, R., & Eickhoff, S. B. (2014). Subtle cognitive deficits in severe alcohol addicts--do they show a specific profile? Journal of Neuropsychology, 8(1), 147-153. https://doi.org/10.1111/jnp.12001 (Original work published 2014)