The Human Mpox Global Outbreak: Available Tools and the Opportunity to Break a Cycle of Neglect in Endemic Countries

Nachega, Jean;Rosenthal, Philip;Rimoin, Anne;Hoof, Nicole;Muyembe, Jean-Jacques;et.al.
(2023) American Journal of Tropical Medicine and Hygiene — Vol. 109, n° 4, p. 719-724 (2023)

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Authors
  • Nachega, Jean
    Author
  • Rosenthal, Philip
    Author
  • Rimoin, Anne
    Author
  • Hoof, Nicole
    Author
  • Hermans, MichelUCLouvain
    Author
  • Muyembe, Jean-Jacques
    Author
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Abstract
(en) The 2022 global outbreak of human Mpox (formerly monkeypox) virus (MPXV) infection outside of the usual endemic zones in Africa challenged our understanding of the virus's natural history, transmission dynamics, and risk factors. This outbreak has highlighted the need for diagnostics, vaccines, therapeutics, and implementation research, all of which require more substantial investments in equitable collaborative partnerships. Global multidisciplinary networks need to tackle MPXV and other neglected emerging and reemerging zoonotic pathogens to address them locally and prevent or quickly control their worldwide spread. Political endorsement from individual countries and financial commitments to maintain control efforts will be essential for long-term sustainability.
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Citations

Nachega, J., Rosenthal, P., Rimoin, A., Hoof, N., Liesenborghs, L., Vanlerberghe, V., Andrei, G., Rawat, A., Wilson, L., Forrest, J., Mills, E., Hermans, M., Mulangu, S., Ntoumi, F., Zumla, A., & Muyembe, J.-J. (2023). The Human Mpox Global Outbreak: Available Tools and the Opportunity to Break a Cycle of Neglect in Endemic Countries. American Journal of Tropical Medicine and Hygiene, 109(4), 719-724. https://doi.org/10.4269/ajtmh.23-0161 (Original work published 2023)