Management of severe cutaneous adverse drug reactions to corticosteroids

Waton, J.;Baeck, Marie;Torres, M.;Barbaud, A.
(2013) Revue Francaise d’Allergologie — Vol. 53, n° 3, p. 298-303 (2013)

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Authors
  • Waton, J.
    Author
  • Baeck, MarieUCLouvain
    Author
  • Torres, M.
    Author
  • Barbaud, A.
    Author
Abstract
Cutaneous adverse drug reactions to corticosteroids (CS) are rare and unexpected. A clinical study including 64 patients (largest global series) plus a review of the literature has allowed us to determine the specific characteristics of this group of patients: majority feminine, a strong predisposition to multiple drug reactions, the possibility of late-onset urticaria, reactions due to systemic long-acting CS, and the existence of DRESS or acute generalized exanthematous pustulosis. These hypersensivities are observed with all CS. Diagnosis cannot be based on common classifications of contact allergy. Our study of the 64 cases provided guidelines for skin testing, re-introduction of CS, and future management of allergic reactions to systemic CS. © 2013 Elsevier Masson SAS.
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Waton, J., Baeck, M., Torres, M., & Barbaud, A. (2013). Management of severe cutaneous adverse drug reactions to corticosteroids. Revue Francaise d’Allergologie, 53(3), 298-303. https://hdl.handle.net/2078.5/205325 (Original work published 2013)