To date, there is no consensus regarding cardiovascular risk management in the very old. Studies have shown that the relationship between traditional cardiovascular risk factors and mortality is null or even inverted within this age group. This relationship could be modified by the presence of frailty. This study was performed to examine the effect of frailty on the association between cardiovascular risk factors and mortality in the oldest old.
Vaes, B., Depoortere, D., Van Pottelbergh, G., Matheï, C., Neto, J., & Degryse, J.-M. (2017). Association between traditional cardiovascular risk factors and mortality in the oldest old: untangling the role of frailty. BMC Geriatrics, 17(1), 234. https://doi.org/10.1186/s12877-017-0626-x (Original work published 2017)