Isomerization issues have been encountered during the ring-closing metathesis (RCM) step of a new approach towards pentalenene. This paper describes the mechanistic insights gained during the study of this side reaction from a substrate perspective. Isomerization issues have been encountered during the RCM step of a new approach towards pentalenene.
De Bo, G., & Marko, I. (2011). Studies towards the Synthesis of Pentalenene: Mechanistic Insights into the Isomerization Phenomenon During RCM of Medium-Sized Rings. European Journal of Organic Chemistry, 2011(10), 1859-1869. https://doi.org/10.1002/ejoc.201001475 (Original work published 2011)