Lung scan in the diagnosis and management of patent foramen ovale pulmonary embolism, paradoxical embolism.

Civelek, A Cahid;Ozalp, Elcin;Gerber, Bernhard;Weiss, James
(2002) Clinical Imaging — Vol. 26, n° 5, p. 349-352 (2002)

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Authors
  • Civelek, A Cahid
    Author
  • Ozalp, Elcin
    Author
  • Author
  • Weiss, James
    Author
Abstract
This case illustrates the reopening of foramen ovale in a young patient with chronic pulmonary hypertension caused by bronchiectasis and chronic pulmonary fibrosis, which resulted in a prominent right-to-left shunt and severe hypoxia. Her clinically unsuspected right-to-left shunt was discovered during ventilation-perfusion scan, which was performed for the evaluation of pulmonary embolism. She had common variable immune deficiency, a primary immunodeficiency disease in which B-lymphocytes produce few or no antibodies. Most patients with this syndrome have an intrinsic defect in their B-lymphocytes that results in reduced immunoglobulin production. In these patients, recurrent respiratory tract infections are common and may result in chronic lung disease, fibrosis, particularly bronchiectasis (20-30%) and even cor pulmonale as happened in our patient [J. Clin. Immunol. 9 (1989) 22-33.].
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Citations

Civelek, A. C., Ozalp, E., Gerber, B., & Weiss, J. (2002). Lung scan in the diagnosis and management of patent foramen ovale pulmonary embolism, paradoxical embolism. Clinical Imaging, 26(5), 349-352. https://doi.org/10.1016/S0899-7071(02)00448-5 (Original work published 2002)