MR elastography of liver fibrosis: preliminary results comparing spin-echo and echo-planar imaging.
(2008) European Radiology : journal of the European Congress of Radiology — Vol. 18, n° 11, p. 2535-2541 (2008)
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- Abstract
- The purpose of this study was to prospectively compare the performance of magnetic resonance (MR) elastography using echo-planar and spin-echo imaging for staging of hepatic fibrosis. Twenty-four patients who had liver biopsy for suspicion of chronic liver disease had MR elastography performed with both spin-echo and echo-planar sequences. At histology, the fibrosis stage was assessed according to METAVIR. The data acquisition time was about 20 min using spin-echo, and only 2 min using echo-planar imaging. The hepatic signal-to-noise ratios were similar on both images (22.51 +/- 5.37 for spin-echo versus 21.02 +/- 4.76 for echo-planar, p = 0.33). The elasticity measurements and the fibrosis stages were strongly correlated. The Spearman correlation coefficients were r = 0.91 (p < 0.01) with spin-echo and r = 0.84 (p < 0.01) with echo-planar sequences. These correlation coefficients did not differ significantly (p = 0.17). A strong correlation was also observed between spin-echo and echo-planar elasticity (r = 0.83, p < 0.001), without systematic bias. The results of our study showed that echo-planar imaging substantially decreased the data acquisition time of MR elastography, while maintaining the image quality and diagnostic performance for staging of liver fibrosis. This suggests that echo-planar MR elastography could replace spin-echo MR elastography in clinical practice.
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Huwart, L., Salameh, N., Ter Beek, L., Vicaut, E., Peeters, F., Sinkus, R., & Van Beers, B. (2008). MR elastography of liver fibrosis: preliminary results comparing spin-echo and echo-planar imaging. European Radiology : journal of the European Congress of Radiology, 18(11), 2535-2541. https://doi.org/10.1007/s00330-008-1051-5 (Original work published 2008)