Patients with airborne sensitization/contact dermatitis from budesonide-containing aerosols 'by proxy'.
(2009) Contact dermatitis — Vol. 61, n° 1, p. 1-8 (2009)
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- BACKGROUND: Inhalation corticosteroids (CSs), despite their wide use, rarely cause sensitization in subjects administering them. OBJECTIVE: To determine the cause of sensitization and/or of allergic contact dermatitis which occurred in air-exposed body areas of patients reacting to corticosteroids and to budesonide, in particular. METHODS: We reviewed the patch test results and sensitization sources in patients who reacted positively to corticosteroids tested in the K.U. Leuven Dermatology department during an 18-year period. RESULTS: Fifteen subjects, not themselves treated by budesonide-containing aerosols, but taking care of/or living together with patients who used them because of a chronic respiratory affection, appeared to have been sensitized by airborne exposure and/or presented with airborne allergic contact dermatitis from them. CONCLUSION: Air exposure to inhalation corticosteroids used 'by proxy' and to budesonide, in particular, needs to be taken into account as a potential cause of primary sensitization and/or airborne allergic contact dermatitis, sometimes also in an occupational context.
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Citations
Baeck, M., & Goossens, A. (2009). Patients with airborne sensitization/contact dermatitis from budesonide-containing aerosols ‘by proxy’. Contact dermatitis, 61(1), 1-8. https://doi.org/10.1111/j.1600-0536.2009.01575.x (Original work published 2009)