Unsymmetrical diarylketones from electron-rich heterocyclic arenes
(2003) Monatshefte für Chemie : an international journal of chemistry — Vol. 134, n° 6, p. 823-830 (2003)
Files
pdfdocument.pdf
Restricted Access - Adobe PDF
- 94.72 KB
Details
- Authors
- Abstract
- AlCl3-mediated chlorocarbonylation of a first arene by oxalyl chloride followed by in situ Friedel-Crafts acylation of a second electron-rich arene expeditiously provides, in a one-pot procedure, either symmetrical or unsymmetrical benzophenones with yields ranging from 17-52%. Best results are obtained when the more activated substrate is used as the second arene. Another advantage is that the resultant benzophenone precipitates from the reaction mixture allowing facile workup.
- Affiliations
Citations
Poupaert, J., Depreux, P., & McCurdy, C. (2003). Unsymmetrical diarylketones from electron-rich heterocyclic arenes. Monatshefte für Chemie : an international journal of chemistry, 134(6), 823-830. https://doi.org/10.1007/s00706-002-0573-9 (Original work published 2003)