Rat chromosome 2 : Assignment of the genes encoding cyclin B1, interleukin 6 signal transducer, and protein convertase 1 to the Mcs1-containing region and identification of new microsatellite markers

Szpirer, Claude;Tissir, Fadel;et.al.
(1999) Mammalian Genome — Vol. 10, n° 1, p. 30-34 (1999)

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  • Szpirer, ClaudeULB
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  • Tissir, Fadelorcid-logoUCLouvain
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  • et. al.
Abstract
The rat Chromosome (Chr) 2 harbors several genes controlling tumor growth or development, blood pressure, and non-insulin-dependent diabetes mellitus. We report that the region (2q1) containing the mammary susceptibility cancer gene Mcs1 also harbors the genes encoding cyclin B1, interleukin 6 signal transducer (gp130), and proprotein convertase 1. We also generated 13 new anonymous microsatellite markers from Chr 2-sorted DNA. These markers, as well as a microsatellite marker in the cyclin B1 gene, were genetically mapped in combination with known markers. A cyclin B1-related gene was also cytogenetically assigned to rat Chr 11q22-q23
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Szpirer, C., Tissir, F., & et al. (1999). Rat chromosome 2 : Assignment of the genes encoding cyclin B1, interleukin 6 signal transducer, and protein convertase 1 to the Mcs1-containing region and identification of new microsatellite markers. Mammalian Genome, 10(1), 30-34. https://hdl.handle.net/2078.5/59113 (Original work published 1999)