Due to its hemodynamic properties and ease of administration (quick induction, rare cough or laryngospasm), Sevoflurane has rapidly become the agent of induction of choice in pediatric patients. However, it can induce troublesome excitation phenomena during induction and awakening and it could have an epileptogenic effect. The mechanisms and strategies to reduce those drawbacks are reviewed.
Veyckemans, F. (2002). Excitation and delirium during sevoflurane anesthesia in pediatric patients. Minerva anestesiologica, 68(5), 402-405. https://hdl.handle.net/2078.5/54609 (Original work published 2002)