Treat-to-target in systemic lupus erythematosus: where are we today?

Mosca, Marta;Boumpas, Dimitrios T;Bruce, Ian N;Cervera, Ricard;van Vollenhoven, Ronald F;et.al.
(2012) Clinical and Experimental Rheumatology — Vol. 30, n° 4 Suppl 73, p. S112-S115 (2012)

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Authors
  • Mosca, Marta
    Author
  • Boumpas, Dimitrios T
    Author
  • Bruce, Ian N
    Author
  • Cervera, Ricard
    Author
  • Houssiau, FrédéricUCLouvain
    Author
  • van Vollenhoven, Ronald F
    Author
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Abstract
Multiple clinical trials performed over twenty years in the treatment of rheumatoid arthritis (RA) have clearly demonstrated that patients have better outcomes if their disease activity at each time-point for follow-up includes a pre-specified target. A European SLE expert panel met in Zurich on May 8, 2012 to discuss whether a treat-to-target approach could be applied in the treatment of systemic lupus erythematosus (SLE) (T2T/SLE), define a research agenda, and establish a plan for moving forward. In the present paper, observations raised at the meeting and literature data on potential therapeutic targets are reported. The working group on T2T/SLE will continue work over the coming year.
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Mosca, M., Boumpas, D. T., Bruce, I. N., Cervera, R., Czirjak, L., Dörner, T., Houssiau, F., Jacobsen, S., Schneider, M., Smolen, J. S., Voskuyl, A. E., & van Vollenhoven, R. F. (2012). Treat-to-target in systemic lupus erythematosus: where are we today? Clinical and Experimental Rheumatology, 30(4 Suppl 73), S112-S115. https://hdl.handle.net/2078.5/95554 (Original work published 2012)