The role of Dopamine in Preparatory Inhibition: What can we learn from Parkinson’s disease?
(2019) 9th International Symposium on Biology of Decision Making (SBDM — Location: (United Kingdom) Oxford (27.May.2019)
Files
2019_Wilhelm_SBDM2019_Absract.pdf
Open Access - Adobe PDF
- 3.49 MB
Details
- Authors
- Abstract
- By measuring the amplitude of motor-evoked potentials (MEPs) elicited by transcranial magnetic stimulation (TMS) over the primary motor cortex during choice reaction time (RT) tasks, many studies have revealed a strong suppression of corticospinal excitability when preparing an action [1-4]. This phenomenon – called “preparatory inhibition” – still remains a matter of investigation and debate: neither its functional role as part of action preparation nor the neural structures at its basis have been clearly elucidated yet [5-9]. Furthermore, this phenomenon has never been investigated in Parkinson’s disease (PD). Yet, it would allow addressing the role of basal ganglia and dopamine in the generation of preparatory inhibition [...]
- Affiliations
Citations
Wilhelm, E., Quoilin, C., Derosiere, G., Jeanjean, A., & Duque, J. (2019). The role of Dopamine in Preparatory Inhibition: What can we learn from Parkinson’s disease? 9th International Symposium on Biology of Decision Making (SBDM, (United Kingdom) Oxford. https://hdl.handle.net/2078.5/93859